Detection of arrhythmias in patients with cardiac amyloidosis using implantable ECG recorders

Abstract Introduction Cardiac Amyloidosis frequently results in congestive cardiac failure and arrhythmias, from a disruption substrate with subsequent electro-mechanical remodeling. Arrhythmias are vary based on the amyloidosis type. Conduction defects atrial arrhythmias more prevalent transthyretin compared light chain amyloidosis, this difference might be reflection of longer survival time former. Methods 112 (TTR) patients completed underlying diagnosis including 99mTc-DPD scan, genetic testing endomyocardioal biopsy (27%) without documented were randomized to standard clinical follow-up or implantation an ECG loop recorder (ILR). The classic FU took place heart clinic, group ILR was monitored by remote control automatic daily report occurrence independent organization. If arrhythmia detected, patient contacted immediately. mean for both groups 17±7 months. Results summarized Table 1. Conclusions Currently, there is no consensus absolute benefit that ICDs amyloidosis. When non-sustained VT syncope captured documented, ICD prevention SCD CA most likely reasonable approach. However, intensive monitoring using can lead accurate early detection ventricular particular initiation treatment as SCD. Documentation significantly higher (p<0.005) clear predictor (HR 2.51). Funding Acknowledgement Type funding sources: None.